Relation between IFCC numbers and the respective national DCMs
The relations can be expressed either as conversion formulas or as
HbA1c numbers at given clinical conditions.
Conversion factors| National DCM |
From IFCC to DCM |
From DCM to IFCC |
|---|
| NGSP (USA) |
NGSP = 0.09148 IFCC + 2.152 |
IFCC = 10.93 NGSP - 23.50 |
| JDS/JSCC (Japan) |
JDS = 0.09274 IFCC + 1 .724 |
IFCC = 10.78 JDS - 18.59 |
| Mono-S (Sweden) |
Mono-S = 0.09890 IFCC + 0.884 |
IFCC = 10.11 Mono-S - 8.94 |
Source: Hoelzel W, Weykamp C, Jeppsson JO, Miedema K, Barr JR, Goodall I, Hoshino T, John WG, Kobold U, Little R, Mosca A, Mauri P, Paroni R, Susanto F, Takei I, Thienpont L, Umemoto M, Wiedmeyer HM. IFCC Reference System for Measurement of Hemoglobin A1c in human blood and the national standardization schemes in the United States, Japan and Sweden: a method comparison study.
Clin.Chem. 2004; 50: 166-174
Published Clinical Targets and Reference Ranges, expressed in IFCC and DCM numbers, respectively
| Clinical Condition |
IFCC |
NGSP |
JDS/JSCC |
Mono-S |
|---|
| Upper level of non-diabetic reference range |
43 mmol/mol |
6.1 % |
5.7 % |
5.1 % |
| ADA target for patients with diabetes |
53 mmol/mol |
7.0 % |
6.6 % |
6.1 % |
